|
The antidepressant drug doxepin has been associated with a number of different adverse effects, including the following. The incidence of these adverse effects is not totally known as the scarcity of well-designed clinical trials involving doxepin prohibits it. Side effects that are common (based on its pharmacology or the frequency of these side effects with related agents) appear with a * superscript whereas the side effects which are serious are in bold. * Nausea * * Dizziness * * Drowsiness * * Dry mouth * * Constipation * * Blurred vision * * Headache * * Urinary hesitancy * * Agitation * * Insomnia * * Sexual dysfunction * * Hypotension (low blood pressure) * Hypertension (high blood pressure) * Tachycardia (high heart rate) * Skin rash * Facial oedema * Photosensitisation * Urticaria (hives) * Pruritus (itching) * Indigestion * Bone fractures * Taste disturbances * Diarrhoea * Anorexia (weight loss) * Aphthous stomatitis (canker sores) * Gynaecomastia (swelling of the breasts in men) * Galactorrhoea (lactation that is unassociated with breast feeding or pregnancy) * Chills * Fatigue * Weakness * Flushing * Alopecia (hair loss) * Eosinohpilia * Blood dyscrasias (abnormalities in the cellular composition of blood) * Increased liver function tests * Hyperpyrexia (high fever ≥41.5°C or 106.7°F) * Seizures * Confusion * Malaise * Increased appetite * * Changes in ECG parameters (e.g. QRS & PR interval) * Ataxia * Hallucinations * Paraesthesias * Nervousness * Numbness * Tinnitus * Hepatitis (liver swelling) * Exacerbation of asthma * Hepatic (liver) abnormalities * Urinary retention * Extrapyramidal symptoms * Testicular swelling * Hyperglycaemia (high blood sugar) * Hypoglycaemia (low blood sugar) * Hyponatraemia (low blood sodium) * Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) * Closed-angle glaucoma * Alzheimer's disease or dementia * ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「List of adverse effects of doxepin」の詳細全文を読む スポンサード リンク
|